Add a healthy dose of design to your upcoming travels with these luxurious and affordable accommodations.

1. The Eliza Jane

Location: New Orleans, Louisiana

Manhattan–based interior design firm Stonehill Taylor has converted a row of 19th-century warehouses in New Orleans into the The Eliza Jane, a boutique hotel elegantly dressed in homage to the area’s cultural and architectural heritage.

The team has woven references to these original occupants throughout the interior while emphasizing one standout tenant—Eliza Jane Poitevent, the first woman publisher of a major metropolitan newspaper in the U.S., who helmed The Daily Picayune in the late 1800s.

2. La Casa Pequena

Location: Oaxaca, Mexico

"Raw, unadulterated and entirely at one with nature, we love how two distinct themes can environmentally coexist here," says BoutiqueHomes.

"Inspired by Thoreau’s Call of the Wild, this beach house rental along the Oaxacan coast is a modern homage to simple living that will inspire you to unplug and reconnect with nature. Down a rambling dirt road in what feels like the middle of nowhere, there stands a striking structure that blends a refined, modern design aesthetic with a raw, primitive spirit. Just a short distance from the surfing mecca of Puerto Escondido in coastal Oaxaca, the property inhabits a solitary spot in the jungle scrub opening out to a private and wild shoreline all your own."

3. Eastwind Hotel & Bar

Location: Windham, New York

Eastwind is a year-round boutique hotel nestled on a quaint hillside, surrounded by the beautiful landscape of the Catskill Mountains. The Scandinavian-inspired hotel opened in 2018 after extensive remodeling by the owners. Bjorn Boyer, one of the co-founders, says, "We wanted to create a cozy space where you can curl up after a day of hiking or skiing, and just relax."

The hotel boasts 19 accommodation options, including three "Lushna" cabins and Eastwind's take on glamping.

4. The Slow

Location: Bali, Indonesia

A new kind of hotel has sprung up on the Canggu beach in southern Bali. The Slow—the brainchild of George Gorrow, the designer behind streetwear label Ksubi, and his wife Cisco, a model—combines art, fashion, music, and food for an immersive experience that blends Indonesian and contemporary surf cultures.

George collaborated with architect Rieky J. Sanur of GFAB Architects to create the work of "Tropical Brutalism." The 12-room hotel presents a striking facade of native Bangkirai hardwood screens, chosen for its resilience in tropical climes. Inside, local materials and area-produced crafts and furniture create a warm, textured atmosphere that displays George and Cisco’s personal art collection of over 90 pieces.

5. Moosham 13

Location: Grafenau, Germany

Business analyst Reinhold Windorfer returned to his parents’ 19th-century dairy farm with some 21st-century ideas about how to turn a profit: sell the cows, overhaul the crumbling farmhouse, and open a pair of vacation rentals for travelers to come visit.

Rather than restore what had been, Reinhold proposed a new design and business, based on the growing popularity of farm stays. He converted part of the home into a pair of vacation rentals, offering tourists a chance to experience the same simple pleasures that had drawn him back to the countryside after eight years in the city.

6. Villa Lena Agriturismo

Location: Palaia, Italy

A unique "agri-turismo" located in the heart of rural Tuscany combines holiday accommodation, a farm-to-table restaurant, and a non-profit art foundation. Originally agricultural buildings, stables, and/or hunting lodges, each apartment has been renovated to be comfortable yet retain its historic farmhouse functionality.

Rooms are furnished with locally sourced vintage furniture, antiques, and recycled hand-painted fabrics styled by French designer Clarisse Demory. Fresh and uncluttered, these apartments offer the comfort of a holiday home and display original artworks from the Villa Lena Foundation collection.

7. The Siren Hotel

Location: Detroit, Michigan

Overhauled by design development firm ASH NYC, an early 20th-century Renaissance Revival building in downtown Detroit that once housed the famous Wurlitzer Company has become The Siren Hotel.

Opened in March 2018, The Siren has 106 colorful guest rooms, a carefully curated food, beverage, and retail program, and one of Detroit's only rooftop bars with views into Comerica Park.

8. Isleta El Espino

Location: Isletas de Granada, Nicaragua

Foraging for mangoes, dipping into the pool, gazing out at a misty volcano—if any of this sounds like your idea of paradise, then a trip to Isleta El Espino on Lake Nicaragua is most definitely in order. Co-owned by brother and sister duo Andrew and Kristin Werner, this three-room property embodies idyllic luxury in an eco-conscious setting, offering the serenest of island experiences.

This rental is an intimate place to stay, home to just two thatched-roof treehouses and one bungalow, so by the time you leave, everyone there will know you by name.

9. The Modern Hotel and Bar

Location: Boise, Idaho

The Modern Hotel is a re-animated Travelodge located in downtown Boise’s Linen District. Their bar has classic, crafted cocktails, a talented chef, local music, and a courtyard for warm summer nights under a sea of stars. The space also features 39 intelligently designed rooms with high-tech finishes, making traveling easy and low-stress.

Centered in the city yet close to many of Idaho's natural beauty, the Modern is a home-away-from-home for any weekenders, explorers, risk-takers, and dreamers who value stylish design, quality entertainment, a sociable atmosphere, and ridiculously comfortable beds.

10. Monocabin

Location: Ialisos, Greece

From its stunningly sleek interior to its Hellenic whitewash exterior, the Monocabin embodies Greek island architecture in more ways than one. Designed by Milan–based studio Mandalaki as a prototype for a series of tiny homes, this 280-square-foot retreat is located in the relaxing oasis of Rhodes—the largest of the Dodecanese island chain in Greece—and is just steps away from the Aegean Sea.

11. Ace Hotel New Orleans

Location: New Orleans, Louisiana

"There’s no place in the American South better suited to the Ace aesthetic than New Orleans, perhaps the most colorful city in the country," says Tablet Hotels. "And it’s hard to imagine a better building for the task than this Twenties Art Deco edifice, in the newly revitalized Warehouse District. Ace’s favorite designers, Roman and Williams, had plenty to work with here, a richly detailed backdrop for their trademark eclecticism. The result is predictable, in a good way: it’s more or less what you’d expect when America’s hippest hoteliers set up shop in one of America’s coolest cities. Rooms come with high ceilings, an underrated benefit of industrial spaces, as well as a mix of vintage-style fixtures, authentic vintage furniture, and locally sourced artwork. Tivoli radios are included as a matter of course, and some of the better rooms have turntables and/or Martin acoustic guitars, in case you’re in the mood to stage your own private Jazz Fest."

12. Play Design Hotel

Location: Taipei, Taiwan

Interactive designer Daniel Chen is the brains behind this experimental, five-room boutique hotel—and runner-up in the 2017 Radical Innovation Awards—that connects travelers with Taiwanese designers, many of whom would otherwise struggle with tapping into international markets.

Located on the fifth floor of an unassuming building in Datong district, the Play Design Hotel is a hidden gem with only a small sign to announce its presence. Polished concrete walls and floors coupled with large, black, metal-framed windows create an elegant backdrop for the hand-picked design objects sourced from over 100 local designers.

13. Eden Locke

Location: Edinburgh, Scotland

Following an acclaimed launch in London, Locke Hotels brings its innovative concept to Edinburgh with the opening of Eden Locke. Located on the fashionable George Street, the six-story building—an 18th-century Georgian mansion with a 20th-century extension—was gutted and renovated by New York City–based firm Grzywinski+Pons.

Each of the 72 studio rooms is equipped with a well-stocked kitchen and a living area with smart TV, offering guests the comforts of apartment living with the amenities of a design-forward boutique hotel.

14. The Fleming Hotel

Location: Hong Kong, Hong Kong

International design agency A Work of Substance spearheaded the renovation of the 66-room boutique hotel, which was built in the 1970s and is located in Hong Kong's vibrant Wan Chai neighborhood.

Nostalgic and refined, the hotel’s new design concept draws inspiration from the island's maritime locale and history—and more specifically, the iconic Star Ferry, which transported travelers across the harbor from Kowloon to Hong Kong.

15. Ace Hotel Pittsburgh

Location: Pittsburgh, Pennsylvania

"The local creative and artistic types don’t just patronize the Ace hotels, they take part in creating them," says Tablet Hotels. "And in this monumental, century-old former YMCA building in the city’s East Liberty district, they’ve found a potent symbol of the one-time greatness to which Pittsburgh has lately returned. The ornate architecture certainly provides some visual interest. Against that backdrop, the Ace’s rooms are simple, spare, bright, and sunny—they feel comfortably lived-in and yet somehow crisply brand-new at the same time. Safe to say it all feels cozier and more handmade than the typical Steel City clichés would have it."

16. Numeroventi

Location: Florence, Italy

A collaboration between entrepreneur and former graphic designer Martino di Napoli Rampolla and Alessandro Modestino Ricciardelli, Numeroventi was born when they enlisted Openhouse Magazine editor and interior designer Andrew Trotter to redesign the interiors of the atmospheric palazzo. The result is a 3,000-square-foot creative residency space for artists with loft apartments that are available to rent for around $105 to $144 per night.

Architect Gianni Emiliani was called on to renovate the 16th-century structure with the intention of maximizing natural light and opening up the spaces within the rooms and studios. Trotter infused the interiors with a dose of Scandinavian minimalism and dotted the space with both modern furnishings and midcentury finds.

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La Casa Pequena